CJC-1295 without DAC is a 29-amino acid tetrasubstituted peptide analog of Growth Hormone Releasing Hormone (GHRH), engineered without the Drug Affinity Complex (DAC) modification. It is designed for short-duration receptor binding studies in controlled experimental models.
Molecular Data
Molecular Formula: C₁₅₂H₂₅₂N₄₄O₄₂S
Molecular Weight: 3367.97 Da
Amino Acid Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg
Sequence Length: 29 amino acids
Physical Form: White lyophilised powder
Solubility: Soluble in water and bacteriostatic water
Research Context
CJC-1295 without DAC is referenced in preclinical research examining GHRH receptor binding kinetics and somatotropic pathway pulsatility. The absence of the DAC modification makes it the preferred reference compound when researchers require a shorter-acting GHRH analog to study discrete, time-limited receptor interaction events within controlled experimental models.
Laboratory Applications
Used in in-vitro and preclinical research models examining GHRH receptor binding dynamics, acute somatotropic pathway signalling, and short-duration receptor interaction studies. Standard reference material where time-limited receptor engagement is required by the experimental design.
Storage & Handling
Lyophilised: Store at -20°C
Reconstituted: Aliquot and freeze at -80°C immediately; single-use aliquots recommended
Recommended solvent: Bacteriostatic or sterile water
Peptide is sensitive to repeated thermal cycling — prepare single-use aliquots before freezing
Purity Standard: ≥99.8% (HPLC verified, batch COA provided)
