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profiles Protocol

Compound Profile: Epithalon

Released: 18/04/2026
Analysis Time: 5 minutes
Ref: f4d27d

Research Verification Required

The following documentation is provided strictly for academic and laboratory research purposes. Contents detail molecular properties and in-vitro protocol guidelines. Not for human clinical application.

Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the pineal gland peptide Epithalamin. It is among the most studied short peptides in longevity-focused research, with a long publication history in peer-reviewed in-vitro literature.

Molecular Data

Molecular Formula: C₁₄H₂₂N₄O₉
Molecular Weight: 390.35 Da
Amino Acid Sequence: Ala-Glu-Asp-Gly
Sequence Length: 4 amino acids
Physical Form: White lyophilised powder
Solubility: Soluble in water

Research Context

Epithalon has an extensive preclinical research history, with published in-vitro studies examining its interactions with telomerase pathway activity, replication-associated signalling mechanisms, and cellular senescence markers. It is among the most referenced tetrapeptides in the longevity research literature, making it a well-characterised reference compound for ageing biology research programmes.

Laboratory Applications

Applied in in-vitro research models examining telomerase pathway activity, cellular senescence signalling, and replication-associated biological mechanisms. A standard reference compound for longevity and cellular ageing research panels.

Storage & Handling

Lyophilised: Store at -20°C, away from moisture and light
Reconstituted: Store aliquots at -80°C
Recommended solvent: Sterile water
As a tetrapeptide, Epithalon is relatively stable under standard peptide storage conditions
Avoid prolonged exposure to elevated temperatures post-reconstitution

Purity Standard: ≥99.0% (HPLC verified, batch COA provided)

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