Nicotinamide Adenine Dinucleotide (NAD+) is an endogenous dinucleotide coenzyme present in all living cells and central to a broad range of biological processes. It is among the most studied coenzymes in modern biochemistry.
Molecular Data
Molecular Formula: C₂₁H₂₇N₇O₁₄P₂
Molecular Weight: 663.43 Da
Type: Dinucleotide coenzyme (not a peptide)
Physical Form: White to off-white powder
Solubility: Freely soluble in water
Research Context
NAD+ has an extensive peer-reviewed literature base examining its role in mitochondrial bioenergetics, sirtuin-mediated signalling pathway interactions, and cellular redox state mechanisms. Research interest has expanded significantly in the context of longevity biology, where NAD+ availability has been examined as a variable in cellular senescence studies and mitochondrial function research programmes.
Laboratory Applications
Applicable across a wide range of in-vitro research models examining mitochondrial function, NAD+/NADH redox cycling, sirtuin pathway activity, and cellular energy homeostasis. A foundational reference compound for longevity and metabolic biology research panels.
Storage & Handling
- Store as powder at -20°C in a dry, dark environment
- NAD+ is hygroscopic — reseal containers immediately after use
- Prepare aqueous solutions fresh where possible
- Avoid alkaline pH conditions which accelerate hydrolytic degradation
- Do not store solutions long-term — prepare fresh for each assay where possible
Purity Standard: ≥99.9% (HPLC verified, batch COA provided)
