All incoming research peptide compound vials should be inspected against this protocol before being accepted into laboratory inventory. This procedure ensures that only compliant, uncompromised material enters the research supply chain.
On Receipt
Check the outer packaging for signs of damage, crushing, or temperature excursion indicators (if included).
Record the receipt date and delivery condition in the laboratory goods-in log.
Transfer to appropriate temperature storage immediately — do not leave at room temperature.
Visual Inspection Checklist
Inspect each vial under adequate lighting against a white and black background:
Seal integrity: The crimp cap or rubber stopper should show no signs of tampering, lifting, or damage.
Label verification: Confirm compound name, batch number, and quantity match the order and packing documentation.
Lyophilised cake appearance: The cake should be intact, white or off-white, and firmly formed. Collapsed, powdered, or discoloured cakes indicate possible moisture ingress or thermal excursion.
Vial clarity: Check for cracks, chips, or scratches that could compromise sterility.
Foreign matter: Reject any vial containing visible particulate matter or unusual discolouration.
COA Cross-Referencing
Match the batch number on each vial label against the Certificate of Analysis provided. Verify:
- Compound identity matches
- Purity result meets the stated specification (≥99% minimum)
- HPLC method is documented
- Mass spectrometry confirmation is present
- COA is issued by a named third-party laboratory
Rejection Criteria
Reject and quarantine any vial showing: damaged seal, compromised cake structure, missing or damaged label, or evidence of temperature excursion. Document rejections in the goods-in log and notify the supplier.
